ICSI is a highly sophisticated technique for injecting one single sperm into an egg using microscopic and micromanipulation instruments so it bypasses all the natural barriers that the sperm has to encounter. It is used for couples who have previously failed IVF or when the man has severe infertility problems.

Ovarian stimulation , cycle monitoring and egg collection for ICSI is the same as for conventional IVF. The sperm is prepared on the day of egg collection. The embryologist selects a single viable sperm and injects it directly into a healthy and mature egg. The injected eggs are examined next day for evidence of fertilization. The best embryos ( maximum of 3 ) are transferred into the uterus 3 - 5 days later , any suitable remaining embryos are frozen as in conventional IVF.