Human papillomavirus (HPV) and Chlamydia trachomatis (CT) are the causative agents for the most common sexually transmitted infections in women. Newly introduced laboratory diagnostic procedures for these infectious agents are mostly nucleic acid based, relying on detection and identification of a DNA sequence specific for the infectious agent.

The nucleic acid (DNA) test for HPV and CT detection is the test for detection of the agents in endocervical swab specimens. The test utilizes amplification of target DNA by the Polymerase Chain Reaction (PCR). The nucleic acid (DNA) testing by PCR is sensitive and non-invasive method for determining the presence of an active cervical HPV or CT infection.

Reference

Sin H.L., Veronica S.V., and Suri P., Molecular tests for human papillomavirus (HPV), Chlamydia trachomatis and Neisseria gonorrhoeae in liquid-based cytology specimen. BMC Women’s Health 2009; 9: 8.